Correlation Between Anemia, Sexually Transmitted Infections, and Low Birth Weight Among Pregnant Women
Abstract
Anemia in pregnancy and sexually transmitted infections (STIs) are global health issues linked to low birth weight. This study explored the correlation between these factors and low birth weight at the General Hospital of Scholoo Keyen, South Sorong, Southwest Papua, Indonesia. A cross-sectional observational analytic study was conducted from September 2022 to March 2023, involving pregnant women who gave birth at the General Hospital of Scholoo Keyen. The correlation between risk factors and low birth weight was analyzed using the chi-square test with a significance threshold of p<0.05. Results showed that among 162 pregnant women (average age: 27.72±6.62 years), anemia severity was distributed as follows:severe (3.7%), moderate (16.0%), and mild (40.1%). However, no significant relationship was found between anemia and birth weight (p=0.850, p>0.05). The incidences of HIV, syphilis, and hepatitis B were 3.1%, 13.6%, and 7.4%, respectively. A significant association was identified between HIV infection and low birth weight (p=0.000), while no such association was found for syphilis (p=0.160) or hepatitis B infection (p=0.852). In conclusion, HIV infection is associated with low-birth-weight newborns, but there are no apparent relationships between anemia, syphilis, or hepatitis B infection and low-birth-weight newborns, This study implies the importance of nutritional support among pregnant mothers with HIV and delaying pregnancy in HIV-positive women to until their immune system improve.
Keywords
Anemia, low birth weight, sexually transmitted infections
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- Thapa P, Poudyal A, Poudel R. Prevalence of low birth weight and its associated factors: hospital-based cross-sectional study in Nepal. PLOS Global Public Health. 2022;2(11):e0001220. doi:10.1371/journal.pgph.0001220.
- Wulandari F, Mahmudiono T, Rifqi MA. Maternal Characteristics and socio-economic factors as determinants of low birth weight in Indonesia: analysis of 2017 Indonesian Demographic and Health Survey (IDHS). Int J Environ Res Public Health. 2022;19(21):13892. doi:10.3390/ijerph192113892.
- Sadarang, RAI. The study on low birth weight in Indonesia: Analysis on the 2017 Indonesia Demographic and Health Survey. Jurnal Kesehatan Jambi. 2021;5(2):28-35.
- West Papua Provincial Health Office (WP-PHO). Health profile of West Papua. Manokwari: WP-PHO; 2019.
- Khazaei S, Mansori K, Khazaei Z, Sani M, Ayubi E. Infant and young child feeding status in Iran compared the different United Nation Regions. Int J Pediatr 2016;4:3639-41.
- Figueiredo ACMG, Gomes-Filho IS, Silva RB. Maternal anemia and low birth weight: a systematic review and meta-analysis. Nutrients. 2018;10(5):601. doi:10.3390/nu10050601.
- Tabrizi Moghaddam F, Barjasteh S. Maternal hemoglobin levels during pregnancy and their association with birth weight of neonates. Iran J Ped Hematol Oncol. 2015;5(4):211–7.
- Sibuea R, Raja SNL. Correlation of anemia in pregnancy and low birth weight in public health centers. Sci Midwifery. 2022;10(4):2985–91.
- Medina-Marino A, Cleary S, Muzny CA. Sexually transmitted infection screening to prevent adverse birth and newborn outcomes: study protocol for a randomized-controlled hybrid-effectiveness trial. Trials. 2022;23(1):441. doi:10.1186/s13063-022-06400-y.
- Fentie EA, Yeshita HY, Bokie MM. Low birth weight and associated factors among HIV positive and negative mothers delivered in northwest Amhara region referral hospitals, Ethiopia, 2020: a comparative cross-sectional study. PLoS One. 2022;17(2):e0263812. doi: 10.1371/journal.pone.0263812.
- Bhattacharya D, Guo R, Tseng CH. Maternal HBV viremia and association with adverse infant outcomes in women living with HIV and HBV. Pediatr Infect Dis J. 2021;40(2):e56-e61. doi:10.1097/INF.0000000000002980.
- Wan Z, Zhang H, Xu H. Maternal syphilis treatment and pregnancy outcomes: a retrospective study in Jiangxi Province, China. BMC Pregnancy Childbirth. 2020;20(1):648. doi:10.1186/s12884-020-03314-y.
- Engidaw MT, Eyayu T, Tiruneh T. The effect of maternal anaemia on low birth weight among newborns in Northwest Ethiopia. Sci Rep. 2022;12:15280.
- Stangret A, Wnuk A, Szewczyk G, Pyzlak M, Szukiewicz D. Maternal hemoglobin concentration and hematocrit values may affect fetus development by influencing placental angiogenesis. J Matern Fetal Neonatal Med. 2017;30(2):199-204. doi:10.3109/14767058.2016.1168395.
- Sah SK, Sunuwar DR, Baral JR, Singh DR, Chaudhary NK, Gurung G. Maternal hemoglobin and risk of low birth weight: A hospital-based cross-sectional study in Nepal. Heliyon. 2022;8(12):e12174. doi:10.1016/j.heliyon.2022.e12174.
- Zenebe A, Eshetu B, Gebremedhin S. Association between maternal HIV infection and birthweight in a tertiary hospital in southern Ethiopia: retrospective cohort study. Ital J Pediatr. 2020;46(1):70. doi:10.1186/s13052-020-00834-3.
- Yingjuan L, Peng J, Liu Y. Association between maternal HIV infection and the risks of preterm birth and low birth weight in Chengdu, China: a propensity score matching approach. BMJ Open. 2023;13(9):e071205. doi:10.1136/bmjopen-2022-071205.
- Shodikin MA, Kusumastuti I, Indasyah WA. The Correlation Between Human Immunodeficiency Virus (HIV) Infection in Pregnancy and Low Birth Weight Infants. JHS. 2021;14(3):209–13. doi: 10.33086/jhs.v14i3.2186
- Cui AM, Cheng XY, Shao JG, Li HB, Wang XL, Shen Y, et al. Maternal hepatitis B virus carrier status and pregnancy outcomes: A prospective cohort study. BMC Pregnancy Childbirth. 2016;16:87. doi: 10.1186/s12884- 016-0884-1.
- Bajema KL, Stankiewicz Karita HC, Tenforde MW, Hawes SE, Heffron R. Maternal hepatitis B infection and pregnancy outcomes in the United States: a population-based cohort study. Open Forum Infect Dis. 2018;5(6):ofy134. doi: 10.1093/ofid/ofy134.
- Tan J, Huang S, He G, Tang L, Ren Y, Zheng J, et al. Maternal hepatitis B surface antigen carrier status and its impact on neonatal outcomes: A cohort study of 21 947 singleton newborns in China. J Matern Fetal Neonatal Med. 2017;30(18):2219–24. doi: 10.1080/14767058.2016.1243098.
- Sirilert S, Traisrisilp K, Sirivatanapa P, Tongsong T. Pregnancy outcomes among chronic carriers of hepatitis B virus. Int J Gynaecol Obstet. 2014;126(2):106–10. doi: 10.1016/j.ijgo.2014.02.019
- Sun M, Luo M, Wang T, Zhong T, Chen Q, Liu H. Associations between maternal syphilis infection during pregnancy and low birth weight and preterm birth: a prospective cohort study. Arch Gynecol Obstet. 2024;310(1):203-211. doi:10.1007/s00404-023-07321-0
- da Silva HBM, de Cássia Ribeiro-Silva R, Junior EPP, Barreto ML, Paixão ES, Ichihara MY. Syphilis in pregnancy and adverse birth outcomes: A nationwide longitudinal study in Brazil. Int J Gynaecol Obstet. 2024;166(1):80-89. doi:10.1002/ijgo.15561
- Tsai S, Sun MY, Kuller JA, Rhee EHJ, Dotters-Katz S. Obstet Gynecol Surv. 2019;74(9):557-564. doi:10.1097/OGX.0000000000000713
DOI: https://doi.org/10.15395/mkb.v57.4212
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