Perbedaan Efektivitas Iodine Povidone 1% dengan Listerine® sebagai Preparat Perawatan Mulut terhadap Pencegahan Ventilator Associated Pneumonia
Abstract
Differences in Effectiveness of Iodine Povidone 1% and Listerine® as Oral Care Preparations in Preventing Ventilator-Associated Pneumonia
Oral care is one way to prevent VAP in patients using mechanical ventilation. x This study aimed to determine the prevalence of VAP and the effectiveness of antiseptic preparations in the oral care of intubated patients to prevent ventilator associated pneumonia (VAP). The study used a randomized, single-blind clinical trial in 36 mechanically ventilated patients admitted to the ICU of Dr. Moewardi in February –May 2017. The samples were divided into two groups, namely the 1% povidone-iodine group and Listerine®. Initially, oral hygiene was assessed using the simplified oral hygiene index. After that, oral care was performed using one of the preparations. After 48 hours, oral hygiene and clinical pulmonaryindicator score (CPIS) scores were reassessed. VAP occurred when the CPIS score was 6. The Mann-Whitney test and independent t-test analyzed the data. The 1% povidone-iodine group changed oral hygiene scores with a minor difference (0.195) than Listerine® (0.3605). It indicated that Listerine® was more effective in maintaining oral hygiene (p=0.024). Listerine® was significantly more effective in preventing VAP when compared with 1% iodine povidone (p=0.001). There was no significant difference in mortality of VAP positive or negative subjects (p=0.280). In conclusion, the use of Listerine® as an oral care preparation is significantly more effective in preventing VAP compared to 1% iodine povidone.
Keywords
Full Text:
PDFReferences
Chan K, Gomersall C. Pneumonia. Edisi ke-8. Dalam: Bersten A, Handy J, penyunting. Oh’s intensive care manual. British: Butterworth Heinemann Elsevier; 2014. hlm. 419–20.
Hoshijima H, Kuratani N, Takeuchi R, Shiga T, Masaki E, Doi K, dkk. Effects of oral hygiene using chlorhexidine on preventing ventilator- associated pneumonia in critical care settings: a meta-analysis of randomized controlled trials. J Dent Sci. 2013;8:348–57.
Pear S, Stoessel K, Shoemake S. The role of oral care in prevention of hospital-acquired pneumonia. United Kingdom: Roswell; 2011.
Burns K, Carton E, Fitz S, Fitzpatrick F, Lee C, O’Regan A, dkk. Guidelines for the prevention of ventilator-associated pneumonia in adults in Ireland. Dalam Dublin: Health Protection Surveillance Centre. Dublin: Health Protection Surveillance Centre; 2011. hlm. 1–10.
Labeau S, Blot S. Oral Care in intubated patients: necessities and controversies. Annual update in intensive care and emergency medicine. London: Springer; 2014. hlm. 119–28.
Seguin P, Laviolle B, Fizelier C, Dumont R, Veber B, Gergaud S, dkk. Effect of oropharyngeal povidone-iodine preventive oral care on ventilator-associated pneumonia in severely brain-injured or cerebral hemorrhage patients: a multicenter, randomized controlled trial. Crit Care Med J. 2013;42(1):1–7.
Drysdale R. Listerine Mouthwash Benefits. 2016. Tersedia dari: www.healthguidance.org/entry/5898/1/Listerine-Mouthwash-Benefits.html.
Houston S, Hougland P, Anderson J. effectiveness of 0.12% chlorhexidine gluconate oral rinse in reducing prevalence of nosocomial pneumonia in patient undergoing heart surgery. Am J Crit Care. 2002;11:567–70.
Francoeur K. Timelines of oral care and early-onset ventilator associated pneumonia prevention. [Internet] 2014. Rhode Island College; 2014. Tersedia dari: https://digitalcommons.ric.edu/etd/234/.
Dillon K. Mouthwash for Oral Care and Against Respiratory Infections. [Internet] 2016; Tersedia dari: www.scientiapress.com/mouthwash-oral-respiratory-infections.
Huang KT, Tseng CC, Fang WF, Lin MC. An early predictor of the outcome of patients with ventilator-associated pneumonia. Chang Gung Med J. 2010;33(3):274–82.
Andini AR, Harahap MS. Pengaruh pemberian povidone iodine 1% sebagai oral hygiene terhadap jumlah bakteri orofaring penderita dengan ventilator mekanik. J Kedokteran Universitas Diponegoro. 2012;2(1):1–9.
Chen Y, Wong RWK, Seneviratne CJ, Hagg U, McGrath C, Samaranayake LP. Comparison of the antimicrobial activity of listerine and corsodyl on orthodontic brackets in vitro. Am J Ortho Dentofac Orthoped. 2011; 140(4); 537–42.
DOI: https://doi.org/10.15851/jap.v9n3.2434
Article Metrics
Abstract view : 886 timesPDF - 420 times
This Journal indexed by
JAP is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
View My Stats