Perbedaan Efektivitas Iodine Povidone 1% dengan Listerine® sebagai Preparat Perawatan Mulut terhadap Pencegahan Ventilator Associated Pneumonia
Abstract
Differences in Effectiveness of Iodine Povidone 1% and Listerine® as Oral Care Preparations in Preventing Ventilator-Associated Pneumonia
Oral care is one way to prevent VAP in patients using mechanical ventilation. x This study aimed to determine the prevalence of VAP and the effectiveness of antiseptic preparations in the oral care of intubated patients to prevent ventilator associated pneumonia (VAP). The study used a randomized, single-blind clinical trial in 36 mechanically ventilated patients admitted to the ICU of Dr. Moewardi in February –May 2017. The samples were divided into two groups, namely the 1% povidone-iodine group and Listerine®. Initially, oral hygiene was assessed using the simplified oral hygiene index. After that, oral care was performed using one of the preparations. After 48 hours, oral hygiene and clinical pulmonaryindicator score (CPIS) scores were reassessed. VAP occurred when the CPIS score was 6. The Mann-Whitney test and independent t-test analyzed the data. The 1% povidone-iodine group changed oral hygiene scores with a minor difference (0.195) than Listerine® (0.3605). It indicated that Listerine® was more effective in maintaining oral hygiene (p=0.024). Listerine® was significantly more effective in preventing VAP when compared with 1% iodine povidone (p=0.001). There was no significant difference in mortality of VAP positive or negative subjects (p=0.280). In conclusion, the use of Listerine® as an oral care preparation is significantly more effective in preventing VAP compared to 1% iodine povidone.
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DOI: https://doi.org/10.15851/jap.v9n3.2434
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