Perbandingan Waktu Induksi, Perubahan Tekanan Darah, dan Pulih Sadar antara Total Intravenous Anesthesia Profopol Target Controlled Infusion dan Manual Controlled Infusion

Abstract

Target controlled infusion (TCI) memberikan kemudahan bagi dokter anestesi dalam pelaksanaan total intravenous anesthesia (TIVA). Penelitian ini bertujuan untuk membandingkan waktu induksi, perubahan tekanan darah, dan waktu pulih sadar antara TIVA propofol TCI dan manual controlled infusion (MCI) pada ekstirpasi fibroadenoma payudara. Penelitian dilakukan terhadap 32 wanita (18–40 tahun), status fisik ASA I, yang menjalani operasi ekstirpasi fibroadenoma payudara di Rumah Sakit Dr. Hasan Sadikin Bandung pada bulan Juli–September 2012, secara uji acak terkontrol buta tunggal dalam anestesi umum. Subjek dibagi menjadi dua kelompok yaitu 16 orang dilakukan anestesi umum dengan TIVA propofol TCI dan 16 orang dengan TIVA propofol MCI. Waktu induksi TCI (61,44 detik) lebih singkat daripada MCI (78,5 detik) dan perubahan tekanan darah pada TCI (15,6 %) lebih kecil daripada MCI (24,1%). Tidak berbeda bermakna (p>0,05) dalam hal waktu pulih sadar pada kedua kelompok (TCI 8,95 menit dan MCI 9,90 menit). Simpulan, TIVA propofol TCI memberikan waktu induksi yang lebih singkat dan perubahan tekanan darah yang lebih kecil bila dibandingkan dengan TIVA MCI, namun tidak didapatkan perbedaan dalam hal waktu pulih sadar.

Kata kunci: Manual controlled infusion target controlled infusion, waktu induksi, waktu pulih sadar

Comparison of Induction Time, Changes in Blood Pressure, and Emergence between Target Controlled Infusion and Manual Controlled Infusion of Propofol Total Intravenous Anesthesia

Abstract

Target controlled infusion (TCI) offers anesthesiologists an easier way to conduct total intravenous anesthesia (TIVA). This study was done to compare the induction time, blood pressure and recovery time between propofol TIVA with TCI and the manual controlled infusion (MCI) in patients undergoing breast fibroadenoma extirpation. This study was done on 32 women (aged 18–40 years old), ASA I physical status, who underwent breast fibroadenoma extirpation in Dr. Hasan Sadikin Hospital Bandung within July–September 2012, by single blind randomized controlled trial in general anesthesia. Subjects were allocated into 2 groups, the TCI and MCI group, each consisted of 16 women. TCI’s induction time (61.44 seconds) were much shorter compared to MCI (78.5 seconds) and the blood pressure changes, TCI (15.6%) showed smaller changes compared to MCI (24.1%). There were no significant difference (p>0.05) in the recovery time in both groups (TCI 8.95 minutes and MCI 9.90 minutes). In conclusion, propofol TIVA with TCI showed a shorter induction time and less blood pressure changes compared to MCI, but there was no significant difference in recovery time. The adverse effect of postoperative nausea and vomitting did not occur in both groups.

Keywords: blood pressure changes, induction time, manual controlled infusion, recovery time

DOI: 10.15851/jap.v1n3.194