Characteristics of Brain Imaging in Intracranial Tumor Patients at Neurology Ward Dr. Hasan Sadikin General Hospital Bandung 2017–2019
Abstract
Background: Brain imaging is the main modality in establishing the diagnosis of intracranial tumors. Therefore, by using appropriate imaging modalities, lesions can be identified and this is useful in determining management and monitoring of the therapeutic process. This study aimed to describe the use of imaging modalities and the characteristics of imaging findings in diagnosing intracranial tumor patients.
Methods: This cross-sectional descriptive study obtained data from medical resumes at the Neurology Ward of Dr. Hasan Sadikin General Hospital Bandung, collected by total sampling method. Data on patients with intracranial tumors who underwent imaging examinations in January 2017–December 2019 were taken, including demographical and imaging characteristics data, divided by tumor type.
Results: Of 206 data, the imaging modalities used were contrast CT scan (45.6%), non-contrast CT scan (34.5%), multimodality imaging (13.6%), contrast magnetic resonance imaging (MRI) (3.9%), non-contrast MRI (2.4%), and magnetic resonance spectroscopy (MRS) (0.5%). The most common primary tumor was a solitary lesion (89.4%) located in the right hemisphere in 38.1% of subjects. Metastatic tumors were found mostly as multiple lesions (63.4%) located in both supratentorial and infratentorial in 25.8% of the subjects. Perifocal edema was found in 75% of patients in both tumor types.
Conclusions: Contrast CT scan is the most frequently used imaging modality. The most common radiological finding is perifocal edema. Primary tumors are commonly found in solitary numbers, and are located in supratentorial on the right hemisphere. Metastatic tumors are commonly found in multiple numbers and are located both in supratentorial and infratentorial.
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nternational Agency for Research on Cancer (IARC). Globocan 2020: Indonesia [Internet]. 2020 [cited 2021 January 15]. Available from: https://gco.iarc.fr/today/data/factsheets/populations/360-indonesia-fact-sheets.pdf
Komite Penanggulangan Kanker Nasional Kementerian Kesehatan Republik Indonesia. Panduan penatalaksanaan tumor otak. Jakarta: Kementerian Kesehatan Republik Indonesia; 2016 [cited 2021 January 15]. Available from: http://kanker.kemkes.go.id/guidelines/PPKOtak.pdf
Ostrom QT, Patil N, Cioffi G, Waite K, Kruchko C, Barnholtz-Sloan JS. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2013–2017. Neuro Oncol. 2020;22(12 Suppl 2):iv1–96.
Tabouret E, Chinot O, Metellus P, Tallet A, Viens P, Gonçalves A. Recent trends in epidemiology of brain metastases: an overview. Anticancer Res. 2012;32(11):4655–62.
Minné C, Kisansa ME, Ebrahim N, Suleman FE, Makhanya NZ. The prevalence of undiagnosed abnormalities on non-contrast-enhanced computed tomography compared to contrast-enhanced computed tomography of the brain. S Afr J Rad. 2014;8(1):598.
Gunderman RB. Radiology 101: water. Acad Radiol. 2014;21(7):945–6.
Serkova NJ, Brown MS. Quantitative analysis in magnetic resonance spectroscopy: from metabolic profiling to in vivo biomarkers. Bioanalysis. 2012;4(3):321–41.
Hulmansyah D. Prosedur pemeriksaan magnetic resonance spectroscopy (MRS) kepala pada kasus tumor otak di Instalasi Radiologi RS Awal Bros Pekanbaru. Journal of STIKes Awal Bros Pekanbaru. 2020;1(1):21–30.
Luo Q, Li Y, Luo L, Diao W. Comparisons of the accuracy of radiation diagnostic modalities in brain tumor: a nonrandomized, nonexperimental, cross-sectional trial. Medicine (Baltimore). 2018;97(31):e11256.
Tunthanathip T, Kanjanapradit K, Ratanalert S, Phuenpathom N, Oearsakul T, Kaewborisutsakul A. Multiple, primary brain tumors with diverse origins and different localizations: case series and review of the literature. J Neurosci Rural Pract. 2018;9(4):593–607.
Svokos KA, Salhia B, Toms SA. Molecular biology of brain metastasis. Int J Mol Sci. 2014;15(6):9519–30.
Loeffler JS. Epidemiology, clinical manifestations, and diagnosis of brain metastases. UpToDate [Internet] 2020 [cited 2021 January 15]. Available from: https://www.uptodate.com/contents/epidemiology-clinical-manifestations-and-diagnosis-of-brain-metastases.
Baris MM, Celik AO, Gezer NS, Ada E. Role of mass effect, tumor volume and peritumoral edema volume in the differential diagnosis of primary brain tumor and metastasis. Clin Neurol Neurosurg. 2016;148:67–71.
Hanum A, Achmad BNA, Yueniwati Y, Retnani DP, Setjowati N. Measurement of the peritumoral edema and tumor volume ratio in differentiating malignant primary and metastatic brain tumor. GSC Biol Pharm Sci. 2020;13(2):055–61.
Ledezma CJ, Wintermark M. Modern neuroradiology relevant to anesthetic and perioperative management. In: Cottrell JE, Young WL, editors. Cottrell and Young’s neuroanesthesia. 5th Ed. Philadelphia: Mosby; 2010. p. 95–114.
DOI: https://doi.org/10.15850/amj.v8n4.2361
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