Diastolic Blood Pressure as a Predictor of Mortality in Intracerebral Hemorrhage Stroke Patients with Hypertension

Cep Juli; Uni Gamayani; Nur Atik

doi:10.15850/amj.v8n1.2099

Diastolic Blood Pressure as a Predictor of Mortality in Intracerebral Hemorrhage Stroke Patients with Hypertension

Cep Juli, Uni Gamayani, Nur Atik

Abstract

Background: Intracerebral hemorrhage (ICH) stroke contributes to a considerable number of deaths, ranging between 30% and 40% of the overall stroke mortality. The incidence of stroke increases with higher blood pressure. High blood pressure at the onset of ICH stroke is a strong predictor for mortality and morbidity. This study aimed to explore the role of diastolic blood pressure as a predictor of death in ICH stroke patients.

Methods: Data on 113 ICH stroke patients with chronic hypertension were collected from the medical records of patients treated in the Neurology ward of Dr. Hasan Sadikin General Hospital Bandung, Indonesia, in 2019. Data collected were patient characteristics, hypertension status, systolic and diastolic blood pressures, and patient outcome. Analysis was then performed using the Mann-Whitney test.

Results: This study revealed a positive correlation (p=0.031) between diastolic blood pressure and death in ICH stroke patients with chronic hypertension.

Conclusion: High diastolic blood pressure is associated with mortality in ICH stroke patients with chronic hypertension.

Keywords

Diastolic, intracerebral hemorrhage, predictor, stroke, systolic

Full Text:

PDF

References

Zaidi G, Chichra A, Weitzen, Narasimha M. Blood pressure control in neurological ICU patients: what is too high and what is too low?.The Open Critical Care Medicine Journal. 2013:6(Suppl 1:M3): 46-55

Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJB, Culebras A, et al. An updated definition of stroke for the 21st century: a statement or healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013;44(7): 2064-89

Hwang SK, Kim JS, Kim HJ, Hong CK, Yang KH. Antihypertensive treatment of acute intracerebral hemorrhage by intravenous nicardipine hydrochloride: prospective multi-center study. J Korean Med Sci. 2012;27(9):1085-1090

Nakalema I, Kaddumukasa M, Nakibuuka J, Okello E, Sajatovic M, Katabira E. Prevalence, patterns and factors associated with hypertensive crises in Mulago hospital emergency department; a cross-sectional study. Afr Health Sci.2019;19(1):1757-1767

Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan Republik Indonesia. Laporan nasional riset kesehatan dasar (Riskesdas) 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan Republik Indonesia; 2019

Goswami D, Sharma T, Das CK, Choudhury B, Bharadwaj R. Prognostic factors in intracerebral hemorrhage: a hospital based prospective study. Int J Med Res Prof. 2016;2(5):32-39

Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr. JL, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Hypertension. 2003; 42(6):1206-1252

Caplan LR. Introduction and perspective. In: Caplan LR , editor. Caplan's stroke: a clinical approach. 5th ed. Cambridge: Cambridge University Press; 2016. p. 1-18

An SJ, Tae Jung Kim TJ, Yoon BW. Epidemiology, risk factors, and clinical features of intracerebral hemorrhage: an update. J Stroke. 2017;19(1):3-10

Mahdy ME, Ghonimi NA, Elserafy S, Mahmoud W. The NIHSS score can predict the outcome of patients with primary intracerebral hemorrhage. Egypt J Neurol Psychiatr Neurosurg. 2019;55(1):21

Behrouz R, Hafeez S, Miller CM. Admission leukocytosis in intracerebral hemorrhage: associated factors and prognostic implications. Neurocrit Care. 2015;23(3): 370-3

Kongwad LI, Hegde A, Menon G, Nair R. Influence of admission blood glucose in predicting outcome in patients with spontaneous intracerebral hematoma. Front Neurol. 2018; 9: 725

Flint AC, Conell C, Ren X, Banki NM, Chan SL, Rao VA, et al. Effect of systolic and diastolic blood pressure on cardiovascular outcomes. N Engl J Med. 2019;381(3): 243-251

Marik PE, Varon J. Hypertensive crises: challenges and management. Chest. 2007;131(6):1949-1962

Rodriguez MA, Kumar SK, De Caro M. Hypertensive crisis. Cardiol Rev. 2010;18(2):102-7

Seitz RJ, Donnan GA. Recovery potential after acute stroke. Front Neurol. 2015; 6: 238

Vishram JKK, Borglykke A, Andreasen AH, Jeppesen J, Ibsen H, Jørgensen T, et al. Impact of age on the importance of systolic and diastolic blood pressures for stroke risk: the MOnica, Risk, Genetics, Archiving, and Monograph (MORGAM) Project. Hypertension. 2012;60(5):1117-1123.

Parmar P. Stroke: Classification and diagnosis. Clinical Pharmacist. 2018; 10(1):DOI:10.1211/PJ.2018.20204150

DOI: https://doi.org/10.15850/amj.v8n1.2099