Khalid I. AlHussaini Department of Internal Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia Saudi Arabia
Bassam Abdulaziz Alhusaini Faculty of medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia Saudi Arabia
Saad Abdullah Alzmamy Faculty of medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia Saudi Arabia
Omar Abdulaziz Alfozan Faculty of medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia Saudi Arabia
Abdulaziz Mohammed Alnayil Faculty of medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia Saudi Arabia
Turki Sulaiman Algannas Faculty of medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia Saudi Arabia
Turki Yazeed Alassaf Faculty of medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia Saudi Arabia
Osamah A. Hakami Department of Internal Medicine, King Abdullah Medical City in Holy Capital (KAMC-HC), Makkah, Saudi Arabia Saudi Arabia
Awareness and Knowledge of Celiac Disease Among the General Population in Saudi Arabia
Khalid I. AlHussaini, Bassam Abdulaziz Alhusaini, Saad Abdullah Alzmamy, Omar Abdulaziz Alfozan, Abdulaziz Mohammed Alnayil, Turki Sulaiman Algannas, Turki Yazeed Alassaf, Osamah A. Hakami
Abstract
Celiac disease (CD) is an immune-mediated systemic disorder affecting nutrient absorption triggered by both environmental (gluten) and genetic factors. This study aimed to determine the level of awareness and knowledge of CD among the general population of Saudi Arabia. A community-based online cross-sectional study was conducted between August and October 2022 to examine the awareness regarding signs, symptoms, complications, and treatment of celiac disease. Data were collected and analyzed from 1,675 participants distributed across the five regions in Saudi Arabia. Analysis shows that 65.1% of the participants were familiar with the symptoms of celiac disease, and 49.6% confirmed that symptoms, blood tests, and endoscopy are the best way to diagnose celiac disease. The mean awareness score for the study participants was 71.8 (SD 13.9), with 5.2% of the participants needed a better level of awareness. Having a family history of celiac disease was an important predictor of having a higher level of awareness of celiac disease (p<0.001). The general public in Saudi Arabia demonstrates a moderate to high level of awareness of CD, emphasizing the need for extensive efforts to maintain high awareness of CD among the general public.
Keywords
Awareness; Celiac disease, general population, gluten sensitivity, Saudi Arabia
Fasano A, Catassi C. Clinical practice. Celiac disease. N Engl J Med. 2012;367(25):2419–26. doi:10.1056/NEJMcp1113994
Gujral N, Freeman HJ, Thomson AB. Celiac disease: prevalence, diagnosis, pathogenesis and treatment. World J Gastroenterol. 2012;18(42):6036–59. doi:10.3748/wjg.v18.i42.6036
Gweon TG, Lim CH, Byeon SW. [A case of celiac disease]. Korean J Gastroenterol. 2013;61(6):338–42. doi:10.4166/kjg.2013.61.6.338
Aljebreen AM, Almadi MA, Alhammad A, Al Faleh FZ. Seroprevalence of celiac disease among healthy adolescents in Saudi Arabia. World J Gastroenterol. 2013;19(15):2374–8. doi:10.3748/wjg.v19.i15.2374
El-Metwally A, Toivola P, AlAhmary K. The epidemiology of celiac disease in the general population and high-risk groups in Arab Countries: a systematic review. Biomed Res Int. 2020;2020:6865917. doi:10.1155/2020/6865917
Khafagy AA, Qari WK, Filimban SS, Bahalaq AM, Bulkhi AA. A Cross-sectional study of celiac disease awareness in the food industry in the Western Region of Saudi Arabia. Cureus. 2022;14(6):e25613. doi:10.7759/cureus.25613
Alasmari Y, AlgethamI R, Ali N. Prevalence of celiac disease and its associated risk factors among children in the Kingdom of Saudi Arabia: A systematic review. Indo Am J P Sci. 2018;5(11):11593–600.
Alhussain M. Awareness of Celiac Disease among the General Public in Saudi Arabia. Int. J. Celiac Dis. 2021;9:71–6. doi:10.12691/ijcd-9-2-4
Taşkın B, Savlak N. Public awareness, knowledge and sensitivity towards celiac disease and gluten-free diet is insufficient: a survey from Turkey. Food Sci. Technol. 2020;41. doi:10.1590/fst.07420
Madden J. Celiac disease: more common yet “atypical” than previously thought. J Pediatr Neonatal Care. 2016;4:1-6. doi:10.15406/jpnc.2016.04.00123
Hadjivassiliou M, Sanders DS, Grünewald RA, Woodroofe N, Boscolo S, Aeschlimann D. Gluten sensitivity: from gut to brain. Lancet Neurol. 2010;9(3):318–30. doi:10.1016/S1474-4422(09)70290-X
Qasem WA, Roumi AA, Al Mojil K, Sakijha H, AlMughamis N. Awareness of celiac disease among the public in Kuwait: a cross-sectional survey. BMC Res. Notes. 2023;16(1):133. doi:10.1186/s13104-023-06415-x
Aktas G. Establishment the Diagnosis of Celiac Disease. J Coll Physicians Surg Pak. 2019;29(12):1234–5. doi:10.29271/jcpsp.2019.12.1234
Hybenová E, Štofirová J, Mikulajová A. Celiac disease and gluten-free diet. Potravinarstvo. 2013;7doi:10.5219/276
Muggiano F, Quaranta A, Giannantoni I. Major dental clinical pathological manifestation of celiac disease. WebmedCentral Oral Medicine 2013;4(11):WMC004448
Cosnes J, Nion-Larmurier I. [Complications of celiac disease]. Pathologie-biologie. 2013;61(2):e21–6. Les complications de la maladie cœliaque. doi:10.1016/j.patbio.2011.03.004
Fiorilo C. Editorial Note on Celiac Disease. J. Clin. Gastroenterol. 2021;6(1):1.
Jabeen R. Complications of celiac disease [Internet]. Celiac Disease-From the Bench to the Clinic. IntechOpen; 2019. Available from: http://dx.doi.org/10.5772/intechopen.80465.
Zevallos V, Herencia I. The gluten-free diet. Encyclopedia of Food Grains. 2016;2;91–7. doi:10.1016/B978-0-12-394437-5.00086-3
Marciniak M, Szymczak-Tomczak A, Mahadea D, Eder P, Dobrowolska A, Krela-Kaźmierczak I. Multidimensional disadvantages of a gluten-free diet in celiac disease: a narrative review. Nutrients. 2021;13(2):643. doi:10.3390/nu13020643
Raymond N, Heap J, Case S. The gluten-free diet: an update for health professionals. Practical Gastroenterology. 2006;30:1-11.
Zingone F, Capone P, Ciacci C. Celiac disease: Alternatives to a gluten free diet. World J Gastrointest Pharmacol Ther. 2010;1(1):36–9. doi:10.4292/wjgpt.v1.i1.36
Lee A, Iskander J, Gupta N. What’s hot in the red journal this month. Am J Gastroenterol. 2011;106:1407–9. doi:10.1038/ajg.2011.243
Bagri DD, Gupta D, Mathur P. Assessment of parents’ and child’s attitude as barrier to dietary compliance in celiac disease. IJCP. 2016;15:53–8. doi:10.9790/0853-1508065358
Lerner A, Matthias T. Increased knowledge and awareness of celiac disease will benefit the elderly. Int. J. Celiac Dis. 2015;3:112–4. doi:10.12691/ijcd-3-3-6