Correlation between Quality of Life and Gastroesophageal Reflux Disease
Abstract
Gastroesophageal reflux disease (GERD) is a disease characterized by the rise of stomach acid into the esophagus which leads to heartburn and regurgitation. The prevalence of adult GERD cases worldwide is 11-38.8%. This study aimed to determine the correlation between GERD and quality of life among patients affected by this disease. This was a cross-sectional study conducted on 92 GERD patients in Atma Jaya Hospital, Jakarta, Indonesia from April 2018 to June 2018. Two questionnaires, GERD-Q and GERD-HRQL were used in this study. A validation of the Indonesian version of the GERD-HRQL questionnaire was performed prior to this study. The Mann Whitney test was used to identify the correlation between GERD and the quality of life in patients with upper gastrointestinal symptoms. This study indicated that the GERD-HRQL questionnaire showed good validity and reliability. Results showed that there was a correlation between GERD and quality of life (p = 0.005) in patients with upper gastrointestinal symptoms. In conclusion, GERD affects the quality of life of patients affected by this disease.
Korelasi antara Kualitas Hidup dan Penyakit Refluks Gastroesofagus
Gastroesophageal reflux disease (GERD) atau penyakit refluks gastroesofagus adalah penyakit yang ditandai dengan naiknya asam lambung ke kerongkongan yang menyebabkan sensasi terbakar di dada dan regurgitasi. Prevalensi kasus GERD di seluruh dunia pada orang dewasa adalah 11–38,8%. Penelitian ini bertujuan mengetahui korelasi antara GERD dan kualitas hidup di antara pasien yang terkena penyakit ini. Penelitian dilakukan pada 92 pasien GERD di Rumah Sakit Atma Jaya, Jakarta, Indonesia dari April 2018 hingga Juni 2018. Dua kuesioner, GERD-Q dan GERD-HRQL digunakan dalam penelitian ini. Validasi kuesioner GERD-HRQL versi bahasa Indonesia dilakukan sebelum penelitian ini. Analisis uji Mann Whitney digunakan untuk mengidentifikasi korelasi antara GERD dan kualitas hidup pada pasien dengan gejala gastrointestinal bagian atas. Penelitian ini menunjukkan bahwa kuesioner GERD-HRQL memperlihatkan validitas dan reliabilitas yang baik. Hasil penelitian ini juga menunjukkan erdapat korelasi antara GERD dan kualitas hidup (p=0,005) pada pasien dengan gejala gastrointestinal atas. Simpulan, GERD mempengaruhi kualitas hidup pasien yang terkena penyakit ini.
Keywords
Full Text:
PDFReferences
Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol 2013;108(1);108–308.
Bai Y, Du Y, Zou D, Jin Z, Zhan X, Li Z-S, et al. Gastroesophageal reflux disease questionnaire (gerdQ) in real-world practice: a national multicenter survey on 8065 patients. J Gastroenterol Hepatol. 2013;28(4):626–31.
Syam AF, Putri L, Rahardja C, Utari AP, Syam AF. Prevalence of gastroesophageal reflux disease and its risk factors in rural area. Indones J Gastroenterol Hepatol Dig Endosc 2017:18(1):9–14.
Naomi DA. Obesity as Risk factor of gastroesophageal reflux disease. J Majority. 2014:3(7):22–6.
Siregar GA, Halim S, Sitepu RR. Comparison of endoscopic findings with gastroesophageal reflux disease questionnaires (GERDQ) and reflux disease questionnaire (RDQ) for gastroesophageal reflux disease in Medan. Indones J Gastroenterol Hepatol Dig Endosc 2015;16(3):143–7.
Doulami G, Triantafyllou S, Natoudi M, Albanopoulos K, Leandros E, Zografos G, et al. GERD-related questionnaires and obese population: can they really reflect the severity of the disease and the impact of GERD on Quality of Patients’ Life?. Obes Surg. 2015;25(10):1882–5.
Wang R, Zou D, Ma X, Zhao Y, Yan X, Yan H, et al. Impact of gastroesophageal reflux disease on daily life: the Systematic Investigation of Gastrointestinal Diseases in China (SILC) epidemiological study. Health Qual Life Outcomes 2010;8:128.
Maleki I, Masoudzadeh A, Khalilian A, Daheshpour E. Quality of life in patients with gastroesophageal reflux disease in an Iranian population. Gastroenterol Hepatol Bed Bench. 2013;6(2):96–100.
Supriyatin J. Gastroesophageal reflux diseases pada ibu rumah tangga dewasa muda dengan stressor financial keluarga. J Medula. 2013;1(2):89–95.
Suzuki H, Matsuzaki J, Masaoka T, Inadomi JM. Greater loss of productivity among Japanese workers with gastro-esophageal reflux disease (GERD) symptoms that persist vs resolve on medical therapy. Neurogastroenterol Motil. 2014;26(6):764–71.
Kaji M, Fujiwara Y, Shiba M, Kohata Y, Yamagami H, Tanigawa T, et al. Prevalence of overlaps between GERD, FD and IBS and impact on health-related quality of life. J Gastroenterol Hepatol. 2010;25(6):1151–6.
Jang SH, Ryu HS, Choi SC, Lee SY. Psychological factors influence the gastroesophageal reflux disease (GERD) and their effect on quality of life among firefighters in South Korea. Int J Occup Environ Health. 2016;22(4):315–20.
Lee SW, Chang CM, Chang CS, Kao AW, Chou MC. Comparison of presentation and impact on quality of life of gastroesophageal reflux disease between young and old adults in a Chinese population. World J Gastroenterol. 2011;17(41):4614–8.
Yang XJ, Jiang HM, Hou XH, Song J. Anxiety and depression in patients with gastroesophageal reflux disease and their effect on quality of life. World J Gastroenterol. 2015;21(14):4302–9.
Kim YS, Kim N, Kim GH. Sex and gender differences in gastroesophageal reflux disease. J Neurogastroenterol Motil. 2016; 22(4):575–88.
Song EM, Jung HK, Jung JM. The association between reflux esophagitis and psychosocial stress. Dig Dis Sci. 2013;58(2):471–7.
Zavala-Gonzáles MA, Azamar-Jacome AA, Meixueiro-Daza A, Ramos A, Reyes-Huerta JJ, Roesch-Dietlen F, et al. Validation and diagnostic usefulness of gastroesophageal reflux disease questionnaire in a primary care level in Mexico. J Neurogastroenterol Motil. 2014;20(4):475–82.
DOI: https://doi.org/10.15395/mkb.v52n2.2003
Article Metrics
Abstract view : 4677 timesPDF - 1938 times
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
MKB is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
View My Stats