Gambaran Prokalsitonin, Skor SOFA, dan Rasionalitas Pemberian Antibiotik pada Pasien Luka Bakar Berat di RSUP Dr. Hasan Sadikin Bandung Periode Februari–Agustus 2021
Abstract
Overview of Procalcitonin, SOFA Score, and Rationality of Antibiotics Administration to Patients with Severe Burns at Dr. Hasan Sadikin General Hospital Bandung, February–August 2021
Sepsis is currently the leading cause of death in severe burns due to its wide-ranging effects on organ systems. Procalcitonin and sequential organ failure assessment (SOFA) scores can determine the prognosis of septic patients in terms of mortality indicators, early therapy, and evaluation of the therapy given to reduce mortality and morbidity. Correct and accurate use of antibiotics is also essential in improving the patient's prognosis. This study aimed to determine the procalcitonin, SOFA scores, and the rationality of antibiotics administration to patients with severe burns at Dr. Hasan Sadikin General Hospital Bandung. This analytic observational study was conducted on 38 patients hospitalized in the Burn Unit and ICU of Dr. Hasan Sadikin General Hospital Bandung during February–August in 2021. Procalcitonin values supported by SOFA scores may refer to successful antibiotic administration and ceasing therapy in severe burn injury patients. Antibiotic administration to all patients with severe burns in Dr. Hasan Sadikin General Hospital was irrational as it was not based on cultural examination and procalcitonin on the first day of exposure. Clear signs of infection seen from the procalcitonin value, SOFA score, and culture to avoid antibiotic resistance must support rational prophylactic antibiotic administration.
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DOI: https://doi.org/10.15851/jap.v9n3.2579
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