Perbandingan Efektivitas antara Ketamin Kumur dan Lidokain Spray untuk Mengurangi Nyeri Tenggorok, Batuk, dan Serak Pascaekstubasi

Purwoko Purwoko, Muhammad Husni Thamrin, Wahyu Hananto

Abstract


Nyeri tenggorok adalah komplikasi yang sering dikeluhkan pasien setelah penggunaan pipa endotrakeal pada tindakan anestesi umum. Kejadian nyeri tenggorok dapat dikurangi dengan pemberian agen analgetik. Tujuan penelitian ini mengetahui perbedaan efektivitas antara ketamin kumur dan lidokain spray untuk mengurangi nyeri tenggorok pascaekstubasi. Penelitian dilakukan di Instalasi Bedah Pusat dan kamar rawat inap RSUD Dr. Moewardi Surakarta, dimulai pada bulan Februari–Maret 2018. Penelitian ini bersifat eksperimental dengan double blind randomized control trial pada pasien yang dilakukan anestesi umum dan dipasang pipa endotrakea. Uji Mann Whitney U digunakan untuk mengolah data. Kelompok penelitian dibagi menjadi dua, yaitu kelompok ketamin kumur (I) dan lidokain spray (II). Ketamin kumur lebih efektif mengurangi nyeri tenggorokan, batuk, dan suara serak dibanding dengan lidokain spray mulai 1 jam pascaoperasi dan 6 jam pascaoperasi (p<0,05), sedangkan pada 24 jam pascaoperasi lidokain spray memiliki efektivitas yang hampir sama dengan ketamin kumur.


A Comparative Study on Effectiveness of Ketamine Gargle and Lidocaine Spray for Reducing Sore Throat, Cough, and Hoarseness Post-Extubation


Shore throat is a common complication of endotracheal tube placement under general anesthesia. Administering analgesic agents can reduce the incidence of shore throat. The study aimed to determine the difference in effectiveness between ketamine gargle and lidocaine spray to reduce post-extubation sore throat. The study was conducted at the Central Surgical Installation and Inpatient wards of Dr. Moewardi General Hospital Surakarta in February–March 2018. This experimental study used a double-blind, randomized control trial in patients undergoing general anesthesia with endotracheal tube placement. The Mann-Whitney U test was used to process the data. The research group was divided into ketamine gargle (I) and lidocaine spray (II). Ketamine gargle was more effective in reducing sore throat, cough, and hoarseness than lidocaine spray starting 1 hour postoperatively and 6 hours postoperatively (p<0.05). In contrast, at 24 hours, postoperative lidocaine spray was nearly as effective as ketamine gargle.


Keywords


Batuk, ketamin, lidokain, nyeri tenggorok, suara serak

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DOI: https://doi.org/10.15851/jap.v9n3.2464

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