Prevalence and Characteristics of Depression in Chronic Kidney Disease Patients Receiving Hemodialysis: A Cross-Sectional Study

Authors

  • Nadya Fairuz Imsabrina Faculty of Medicine, Muhammadiyah University Semarang, Indonesia
  • Rihadini Rihadini Department of Psychiatry, Faculty of Medicine Muhammadiyah University Semarang, Indonesia
  • Lukman Faishal Fatharani Department of Biomedicine, Faculty of Medicine Muhammadiyah University Semarang, Indonesia

DOI:

https://doi.org/10.15850/ijihs.v14n1.4353

Keywords:

Beck Depression Inventory-II (BDI-II), Chronic Kidney Disease (CKD), Depression, Hemodialysis

Abstract

Background: Chronic Kidney Disease (CKD) causes decreased kidney function, requiring long-term hemodialysis. This condition is often associated with poor prognosis and increased risk of psychiatric diseases, particularly depression.

Objective: To examines the levels of depression among CKD patients receiving hemodialysis at Roemani Muhammadiyah Hospital, Semarang, Indonesia.

Methods: A descriptive cross-sectional study was conducted on a sample of 80 respondents with CKD undergoing hemodialysis. Samples were selected using purposive sampling based on the inclusion criteria. Data collection was conducted in March 2024 using the Beck Depression Inventory-II (BDI-II) instrument and analyzed with GraphPad 9.5.

Results: The results showed that the prevalence of depression among CKD patients undergoing hemodialysis was 83.8%, 11.9%, and 5.0% for minimal, mild, and moderate depression levels, respectively. Depression was more frequently observed in female patients and those over 50 years old. Significant differences were found in the duration of CKD (p=0.03) and hemodialysis (p=0.02) across depression levels, with shorter durations observed in patients with mild depression. However, correlation analysis revealed a weak and non-significant negative relationship between depression scores and duration of hemodialysis.

Conclusion: Most CKD patients receiving hemodialysis experienced minimal depression, followed by mild and moderate depression, with higher occurrence in women and patients aged >50 years. Although significant differences in CKD and hemodialysis duration were observed across depression levels, the overall relationship showed a weak and non-significant negative correlation.

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References

Chen TK, Knicely DH, Grams ME. Chronic kidney disease diagnosis and management: a review. JAMA. 2019;322(13):1294–304. doi:10.1001/jama.2019.14745.

Badan Penelitian dan Pengembangan Kesehatan. Laporan Nasional Riskesdas 2018. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2019.

Aditiawardana, Widodo. Hemodialisis & peritoneal dialisis pada penyakit ginjal kronis. In: Tjokroprawiro A, Setiawan PB, Santoso D, Soegiarto G, Rahmawati LD, editors. Buku Ajar Ilmu Penyakit Dalam. 2nd ed. Surabaya: Airlangga University Press; 2015. p. 484–492.

Bello AK, Okpechi IG, Osman MA, Cho Y, Htay H, Jha V, et al. Epidemiology of haemodialysis outcomes. Nat Rev Nephrol. 2022;18(6):378–95. doi:10.1038/s41581-022-00542-7.

Indonesian Renal Registry. 11th Report of Indonesian Renal Registry 2018. Jakarta: Indonesian Renal Registry; 2018.

Shirazian S, Smaldone AM, Jacobson AM, Fazzari MJ, Weinger K. Improving quality of life and self-care for patients on hemodialysis using cognitive behavioral strategies: a randomized controlled pilot trial. PLoS One. 2023;18(5):e0285156. doi:10.1371/journal.pone.0285156.

Qawaqzeh DTA, Masa’deh R, Hamaideh SH, Alkhawaldeh A, AlBashtawy M. Factors affecting the levels of anxiety and depression among patients with end-stage renal disease undergoing hemodialysis. Int Urol Nephrol. 2023;55(11):2887–96. doi:10.1007/s11255-023-03578-1.

Sakiqi J, Vasilopoulos G, Koutelekos I, Areti T, Fradelos EC, Zyga S, et al. Depression among hemodialysis patients: related factors and the impact of insomnia and fatigue. Cureus. 2022;14(5):e25254. doi:10.7759/cureus.25254.

Wulansari YT, Umbul Wahyuni C. Description of depression symptoms in hemodialysis patients at Jemursari Hospital, Surabaya. Indones J Public Health. 2020;15(3):304–14. doi:10.20473/ijph.v15i3.2020.304-314.

Mazharulhaq, Rafique K, Ahmad Z, Khan AU, Arshad A, Ilyas K. Prevalence of depression in patients on hemodialysis. Int J Health Sci. 2023;7(S1):41–8. doi:10.53730/ijhs.v7nS1.14149.

Mohamed NA, Eraslan A, Kose S. The impact of anxiety and depression on the quality of life of hemodialysis patients in a sample from Somalia. BMC Psychiatry. 2023;23(1):825. doi:10.1186/s12888-023-05312-8.

Khairidina S, Hasan M, Amirsyah M, Syukri M, Lubis RH. Gambaran tingkat depresi terhadap kejadian peningkatan interdialytic weight gain pada pasien penyakit ginjal kronik yang menjalani hemodialisis di Rumah Sakit Umum Dr. Zainal Abidin, Banda Aceh. J Kedokt Syiah Kuala. 2020;20(2):94–103. doi:10.24815/jks.v20i2.18503.

Shanmukham B, Varman M, Subbarayan S, Ravi R, Kumar S, Balasubramanian S, et al. Depression in patients on hemodialysis: a dilapidated facet. Cureus. 2022;14(9):e29253. doi:10.7759/cureus.29253.

Shirazian S, Grant CD, Aina O, Mattana J, Khorassani F, Ricardo AC. Depression in chronic kidney disease and end-stage renal disease: similarities and differences in diagnosis, epidemiology, and management. Kidney Int Rep. 2017;2(1):94–107. doi:10.1016/j.ekir.2016.09.005.

Orzechowski W, Buczek W, Szczerba JE, Gellert R, Rydzewski A, Fiderkiewicz B, et al. Underdiagnosis of major depressive episodes in hemodialysis patients: the need for screening and patient education. J Clin Med. 2021;10(18):4109. doi:10.3390/jcm10184109.

Ahmadi SM, Masjedi-Arani A, Bakhtiari M, Davazdahemamy MH, Mohamadian R. Psychometric properties of Persian version of Beck Depression Inventory in coronary patients. Universa Med. 2019;38(1):33–40. doi:10.18051/UnivMed.2019.v38.33-40.

Kao HY, Chang CC, Chang CF, Chen YC, Cheewakriangkrai C, Tu YL. Associations between sex and risk factors for predicting chronic kidney disease. Int J Environ Res Public Health. 2022;19(3):1219. doi:10.3390/ijerph19031219.

Shi P, Yang A, Zhao Q, Chen Z, Ren X, Dai Q. A hypothesis of gender differences in self-reporting symptom of depression: implications to solve under-diagnosis and under-treatment of depression in males. Front Psychiatry. 2021;12:589687. doi:10.3389/fpsyt.2021.589687.

Li A, Wang D, Lin S, Chu M, Huang S, Lee CY, Chiang YC. Depression and life satisfaction among middle-aged and older adults: mediation effect of functional disability. Front Psychol. 2021;12:755220. doi:10.3389/fpsyg.2021.755220.

Taple BJ, Chapman R, Schalet BD, Brower R, Griffith JW. The impact of education on depression assessment: differential item functioning analysis. Assessment. 2022;29(2):272–84. doi:10.1177/1073191120971357.

Patria B. The longitudinal effects of education on depression: finding from the Indonesian national survey. Front Public Health. 2022;10:1017995. doi:10.3389/fpubh.2022.1017995.

Choi S, Jang SY, Choi E, Park YS. Association between prevalence and severity of chronic kidney disease and employment status: a nationwide study in Korea. BMC Public Health. 2024;24(1):216. doi:10.1186/s12889-023-17338-4.

Munisi H, Sylvester I, Mwakalebela I, Kanenda S, Rudovick L, Mwita M, et al. Depression and chronic kidney disease: a cross-sectional study based at Bugando Medical Centre, Northwestern Tanzania. Pan Afr Med J. 2022;42:297. doi:10.11604/pamj.2022.42.297.31414.

Elkheir HK, Wagaella AS, Badi S, Khalil A, Elzubair TH, Khalil A, et al. Prevalence and risk factors of depressive symptoms among dialysis patients with end-stage renal disease (ESRD) in Khartoum, Sudan: a cross-sectional study. J Family Med Prim Care. 2020;9(7):3639–43. doi:10.4103/jfmpc.jfmpc_1229_19.

Deswima C, Widodo, Yulianti E. Correlation between duration of hemodialysis and depression in chronic kidney disease. J Med Health Stud. 2021;2(2):139–44. doi:10.32996/jmhs.2021.2.2.17.

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Published

2026-06-30

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How to Cite

Prevalence and Characteristics of Depression in Chronic Kidney Disease Patients Receiving Hemodialysis: A Cross-Sectional Study. (2026). International Journal of Integrated Health Sciences, 14(1), 23-29. https://doi.org/10.15850/ijihs.v14n1.4353