Quality of Life in Thalassemia Major Patients: Reliability and Validity of Indonesian Version of TranQol Questionnaire

Billy Ng Setiawan Rachmat Poengoet, Ellyana Sungkar, Tri Damiati Pandji

Abstract


Objective: To determine the validity and reliability of TranQol questionnaire that has been translated into Indonesian to be used in Indonesian thalassemia major patients. The quality of life problems among these patients can be detected earlier because TranQol is more precise compared to the Pediatric Quality of Life Inventory (PedsQLTM), World Health Organization Quality of Life Instruments (WHOQOL), and SF-36 Questionaire.

Methods: This study was conducted in Bandung, Indonesia from October 2015 to March 2016 and used a standard “forward-backward” translation procedure. It involved 60 adults and 73 children who are thalassemia major patients, and 71 parents of patients in Dr. Hasan Sadikin General Hospital. TranQol was processed through forward and backward translation approach and evaluation was conducted by the TranQol author. After the translation process, a cognitive debriefing was performed and the translated TranQol was tested to all subjects.

Results: Cronbach’s alpha >0.7 was used for all TranQol categories. Front validity and content validity testing was performed. The internal validity results showed that some questions were not valid.

Conclusions: TranQol reliability in Indonesian language for every category is good. Validity for TranQol in Indonesian language shows that the translated TranQol is not quite suitable that it still cannot be used.

Keywords: TranQol Indonesia, validity Indonesia, reliability Indonesia

 

DOI: 10.15850/ijihs.v5n2.1011


Keywords


TranQol Indonesia, validity Indonesia, reliability Indonesia

Full Text:

PDF

References


Weatherall DJ. Thalassemia as a global health problem: recent progress towards its control in the developing countries. Ann N Y Acad Sci. 2010;1202(1):17–23.

Nadkarni A, Phanasgaonkar S, Colah R, Mohanty D, Ghosh K. Prevalence and molecular characterization of alpha-thalassemia syndromes among Indians. Genet Test. 2008;12(2):177–80.

Mohanty D, Colah RB, Gorakshakar AC, Patel RZ, Master DC, Mahanta J, et al. Prevalence of β-thalassemia and other haemoglobinopathies in six cities in India: a multicentre study. J Community Genet. 2013;4(1):33–42.

Flint J, Harding RM, Boyce AJ, Clegg JB. The population genetics of the haemoglobinopathies. Baillieres Clin Haematol. 1998;11(1):1–51.

Stastitical data of thalassemia patients in Indonesia. Yayasan Talasemia Indonesia-Perhimpunan Orangtua Penderita Talasemia Indonesia; 2015. [cited 2015 Jan 10]. Available from: http://www.thalassaemia-yti.org/.

Ayoub MD, Radi SA, Azab AM, Abulaban AA, Balkhoyor AH, Bedair S-eW, et al. Quality of life among children with beta-thalassemia major treated in Western Saudi Arabia. Saudi Med J 2013;34(12):1281–6.

Jafari H, Lahsaeizadeh S, Jafari P, Karimi M. Quality of life in thalassemia major: Reliability and validity of the Persian version of the SF-36 questionnaire. J Postgrad Med. 2008;54(4):273–5.

Ansari S, Baghersalimi A, Azarkeivan A, Nojomi M, Hassanzadeh Rad A. Quality of life in patients with thalassemia major. Iran J Ped Hematol Oncol. 2014;4(2):57–63.

Wahyuni MS, Ali M, Rosdiana N, Lubis B. Quality of life assessment of children with thalassemia. Paediatr Indones. 2011;51(3):163–9.

Haghpanah S, Nasirabadi S, Ghaffarpasand F, Karami R, Mahmoodi M, Parand S, et al. Quality of life among Iranian patients with beta-thalassemia major using the SF-36 questionnaire. Sao Paulo Med J. 2013;131(3):166–72.

Ismail M, Chun CY, Yusoff NAM, Shahar S, Manaf ZA, Rajikan R, et al. Quality of life among thalassaemia children, adolescent and their caregivers. Sains Malaysiana. 2013;42(3):373–80.

Klaassen RJ, Alibhai S, Allen MK, Moreau K, Pulcini MM, Forgie M, et al. Introducing the tran qol: a new disease-specific quality of life measure for children and adults with thalassemia major. J Blood Disorders Transf [serial on the internet]. 2013 Jun [cited 2015 Jan 12];5(150):[about 5p.]. Available from: https://www.omicsonline.org/introducing-the-tran-qol-a-new-disease-specific-quality-of-life-measure-for-children-and-adults-with-thalassemia-major-2155-9864.1000150.php?aid=15595

Klaassen RJ, Barrowman N, Merelles-Pulcini M, Vichinsky EP, Sweeters N, Kirby-Allen M, et al. Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major. BJH. 2014;164(3):431–7.


Article Metrics

Abstract view : 1053 times
PDF - 415 times



 

This Journal indexed by

                   

 


Creative Commons License
IJIHS is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License



View My Stats