Characteristics of Eye Tumor in Children

Pieter Juanarta; Mohamad Rinaldi Dahlan; Andri Rezano

Characteristics of Eye Tumor in Children

Pieter Juanarta, Mohamad Rinaldi Dahlan, Andri Rezano

Abstract

Background: Eye tumors are commonly found and fatal among pediatric patients. The immediacy of management depends on the diagnosis, and is increased when the patient’s characteristics are known. This study aims to describe the characteristics of pediatric patients diagnosed with eye tumors.

Methods: This is a descriptive retrospective study using secondary data involving 102 medical records of pediatric patients diagnosed with eye tumors in the National Eye Center Cicendo Eye Hospital Bandung in the period from January 2013 to December 2014.

Results: The characteristics of 102 subjects: 54 (52.9%) were female, 59 (57.8%) were 1 to 4 years old, and 79 (77.5%) were from West Java. The characteristics of the tumors: 42 (41.2%) presented with a chief complaint of leukocoria, 73 (71.6%) were malignant, 68 (66.7%) were retinal, and the most common management was surgery (64.7%). The most common malignant tumor was retinoblastoma (93.2%) while the most common benign tumor was dermoid cyst (31%).

Conclusion: Patients were frequently 1–4 years old and the most common diagnosis were retinoblastoma and dermoid cyst.

DOI: 10.15850/amj.v4n1.970

Keywords

Characteristics, children, eye tumors

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References

Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and cotran pathologic basis of disease, professional ed: Expert Consult - Online. Philadelphia: Elsevier Health Sciences; 2009. p. 677–859.

Kivelä T. The epidemiological challenge of the most frequent eye cancer: retinoblastoma, an issue of birth and death. Br J Ophthalmol. 2009;93(9):1129–31.

Modi PJ, Shah NA, Bhalodia JN, Gonsai RN. Orbital tumors in children : a descriptive study at tertiary care centre. Natl J Med Res. 2013;3(4):362–6.

Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, et al. Cancer statistics, 2005. CA Cancer J Clin. 2005;55(1):10–30.

Ophthalmology AAO. Fundamentals and principles of ophthalmology 2012-2013. Singapore: American Academy of Ophthalmology; 2012. p. 1–455.

Li SY, Chen SCC, Tsai CF, Sheu SM, Yeh JJ, Tsai CB. Incidence and survival of retinoblastoma in Taiwan: a nationwide population-based study 1998–2011. Br J Ophthalmol. 2015;10(1):1–4.

Nemet AY, Deckel Y, Martin PA, Kourt G, Chilov M, Sharma V, et al. Management of periocular basal and squamous cell carcinoma: a series of 485 cases. Am J Ophthalmol. 2006;142(2):293–7.

World Health Organizations. Provisional guidelines on standard international age classifications. New York: Publishing Service United Nations; 1982. p. 32.

Zhao J, Li S, Shi J, Wang N. Clinical presentation and group classification of newly diagnosed intraocular retinoblastoma in China. Br J Ophthalmol. 2011;95(1):1372–5.

Chung EM, Specht CS, Schroeder JW. Pediatric orbit tumors and tumorlike lesions: neuroepithelial lesions of the ocular globe and optic nerve. Radiographics. 2007;27(1):1159–86.

Ramasubramanian A, Shields CL, Kytasty C, Mahmood Z, Shah SU, Shields JA. Resection of intraocular tumors (partial lamellar sclerouvectomy) in the pediatric age group. Ophthalmology. 2012;119(12):2507–13.

Shields CL, Manjandavida FP, Lally SE, Pieretti G, Arepalli SA, Caywood EH, et al. Intra-arterial chemotherapy for retinoblastoma in 70 eyes. Ophthalmology. 2014;121(7):1453–60.

Yousef YA, Finger PT. Squamous carcinoma and dysplasia of the conjunctiva and cornea. Ophthalmology. 2012;119(2):233–40.

Balmer A, Zografos L, Munier F. Diagnosis and current management of retinoblastoma. Oncogene. 2006;25(38):5341–9.

Ophthalmology AAO. Ophthalmic pathology and intraocular tumors: 2009-2010. Singapore: American Academy of Ophthalmology; 2009. p. 251–65.

Lee CS, Rim THT, Kwon HJ, Yi JH, Lee SC. Partial lamellar sclerouvectomy of ciliary body tumors in a Korean population. Am J Ophthalmol. 2013;156(1):36–42.

Broaddus E, Topham A, Singh AD. Incidence of retinoblastoma in the USA: 1975-2004. Br J Ophthalmol. 2009;93(1): 21–3.

Soomro T, Kehar SI, Anwar M. Frequency and morphological patterns of malignant intra orbital tumors in various age groups. Pak J Ophthalmol. 2011;27(4):203–207.

Wilson MW, Halk BG, Billups CA, Galindo CR. Incidence of new tumor formation in patients with hereditary retinoblastoma treated with primary systemic chemotherapy: is there a preventive effect?. Ophthalmology. 2007;114(11):2077–82.

Rahman I, Cook AE, Leatherbarrow B. Mortality following exenteration for malignant tumours of the orbit. Br J Ophthalmol. 2005;89(1):1444–8.