Risk Factors for Febrile Seizures in Children Aged 6 – 59 Months in Surabaya, East Java

Febrianto Adi Husodo, Sitti Radhiah, Pramita Anindya Nugraheni

Abstract


Background: Febrile seizures are common in children under 5 years of age. Parents are concerned when their children have seizures; therefore, it is necessary to provide promotive and preventive education regarding the risk factors for febrile seizures so that parents are more prepared. This study aimed to explore the risk factors for febrile seizures in children.

Methods: This case-control study was conducted on 170 children. Sampling was carried out by purposive sampling on inpatients and/or outpatients at the Pediatric Department Dr. Ramelan Naval Hospital Surabaya during May 2019-July 2020. Secondary data for children with fever were retrieved from medical records, with seizures (n85) and without seizures (n85) as a control group. Furthermore, data on temperature, age, birth weight, and history of asphyxia were analyzed and compared, using the chi-square test or Fisher’s exact test.

Results: There was a significant difference between the case and control groups regarding the history of asphyxia and the occurrence of febrile seizures (p=0.002; OR=26.39; and 95% CI 1.52-455.62). There was no significant difference between the risk factors for high temperature (p=0.12), age (p=0.52), or birth weight (p=0.37) with the occurrence of febrile seizures.

Conclusions: A history of asphyxia in children under five years is a risk factor for febrile seizures. Appropriate education from health professionals can help parents improve their knowledge, attitudes, and practices in dealing with febrile seizures and their risk factors.


Keywords


Children aged 6-59 months, febrile seizure, risk factors

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References


Gaderi I. The risk factors in children with simple and complex febrile seizures: An epidemiological study. Int J Pediatr. 2017;5(6):5137–44.

Jarrett OO, Fatunde OJ, Osinusi K, Lagunju IA. Pre-hospital management of febrile seizures in children seen at the university college hospital, ibadan, Nigeria. Ann Ib Postgrad Med. 2012;10(2):6–10.

Arief RF. Penatalaksanaan kejang demam. Cermin Dunia Kedokteran-232. 2015;42(9):658–61.

Syahida JA, Risan NA, Tarawan VM. Knowledge and attitude on febrile seizure among mothers with under-five children. Althea Medical Journal. 2016;3(4):649–54.

Subcommittee ob Febril Seizures. Clinical practice guideline-febrile seizure: guidelines for the neurodiagnostic evaluation of the child with a simple febrile seizure. Pediatrics. 2011;127(2):389–94.

Patterson JL, Carapetian SA, Hageman JR, Kelley KR. Febrile seizures. Pediatr Ann. 2013;42(12):249–54.

Kakalang JP, Masloman N, Manoppo JICh. Profil kejang demam di Bagian Ilmu Kesehatan Anak RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2014–Juni 2016. e-CliniC. 2016;4(2):14396.

Leung AKC, Hon KL, Leung TNH. Febrile seizures: an overview. Drugs Context. 2018;7:212536.

Nindela R, Dewi MR, Ansori IZ. Karakteristik penderita kejang demam di instalasi rawat inap Bagian Anak Rumah Sakit Muhammad Hoesin Palembang. Jurnal Kedokteran dan Kesehatan. 2014;1(1):41–5.

Fuadi, Bahtera T, Wijayahadi N. Faktor risiko bangkitan kejang demam pada anak. Sari Pediatri. 2010;12(3):142–9.

Einfeld DOS, Pellock JM. Recent research on febrile seizures: a review. J Neurol Neurophysiol. 2013;4(165):19519.

Mikati MA, Tchapyjnikov D. Febrile Seizures. In: Kliegman RM, St Geme III JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, editors. Nelson textbook of pediatrics. 21st ed. Philadelphia: Elsevier; 2020. p. 12071–9.

Feenstra B, Pasternak B, Geller F, Carstensen L, Wang T, Huang F, et al. Common variants associated with general and MMR vaccine-related febrile seizures. Nat Genet. 2014;46(12):1274–82.

Camfield C, Camfield P, Neville B. Febrile seizures. In: Engel J, Pedley TA, editors. Epilepsy: a comprehensive textbook. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2008. p. 659–65.

Francis JR, Richmond P, Robins C, Lindsay K, Levy A, Effler PV, et al. An observational study of febrile seizures: the importance of viral infection and immunization. BMC Pediatr. 2016;16(1):202.

Yousif AB, Hafez LM, Benkhaial FS. Risk factors for febrile seizures in Benghazi, Libya: a case–control study. Alexandria J Pediatr. 2017;30(2):68–73.

Sharawat IK, Singh J, Dawman L, Singh A. Evaluation of risk factors associated with first episode febrile seizure. J Clin Diagn Res. 2016;10(5):SC10–3.

Mahyar A, Ayazi P, Fallahi M, Javadi A. Risk Factors of the First Febrile Seizures in Iranian Children. Int J Pediatr. 2010;2010:862897.

Yahyaoui S, Lammouchi M, Yahyaoui O, Olfa B, Sonia M, Samir B. Risk factors for febrile seizures in Tunisian children : a case-control study. J Med Surg Pathol. 2018;4(3):1–5.

Tsuboi T, Okada S. Exogenous causes of seizures in children: A population study. Acta Neurol Scand. 1985;71(2):107–13.




DOI: https://doi.org/10.15850/amj.v8n3.2351

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