Malnutrition in Non-Hodgkin Lymphoma Patients at Dr. Hasan Sadikin General Hospital Bandung

Azizah Puspitasari Ardinal, Siska Wiramihardja, Indra Wijaya


Background: Non-hodgkin lymphoma (NHL) has the highest prevalence among hematologic malignancies. The prognosis and response to therapy in NHL patients may worsen in the presence of malnutrition. The aim of the study was to describe the malnutrition status in NHL patients.

Methods: This was a cross-sectional descriptive study. Nutritional status was assessed using Subjective Global Assessment (SGA) obtained from the medical records of all NHL patients at Dr. Hasan Sadikin General Hospital registered in 2017.

Results: In total, there were 78 medical records of NHL patients that fulfilled the inclusion criteria. All NHL patients had experienced malnutrition, categorized as mild-moderate malnutrition (70.5%) and severe malnutrition (29.5%). In NHL patients with mild-moderate malnutrition, 29% had 5–10% weight loss; 60% had suboptimal solid diet; 56.4% experienced anorexia; and 50.9% had subcutaneous fat loss. In NHL patients with severe malnutrition, 78.3% had more than 10% weight loss; 73.9% had suboptimal solid diet; 78.3% experienced anorexia; and 100% had subcutaneous fat loss.

Conclusions: Based on subjective assessment, all NHL patients were malnourished and experienced change of food intake and loss of subcutaneous fat, therefore, a better nutritional support scheme are crucial for NHL patients.


Non-hodgkin lymphoma, malnutrition, subjective global assessment

Full Text:



Reksodiputro AH, Irawan C. Limfoma non-hodgkin (LNH). In: Setiati S, Alwi I, Sudoyo AW, Simadibrata KM, Setiyohadi B, Syam AF, editors. Buku Ajar Ilmu Penyakit Dalam Jilid 3. 6th ed. Jakarta: Interna Publishing; 2014. p. 2977-93.

International Association of Cancer Registries, World Health Organization. Global cancer observatory: cancer today. Lyon, France: International Agency for Research on Cancer (IARC); 2018.

Planas M, Alvarez-Hernandez J, Leon-Sanz M, Celaya-Perz S, Araujo K, Harcia de Lorenzo. Prevalence of hospital malnutrition in cancer patients: a sub-analysis of the PREDyCES® study. Support Care Cancer. 2016;24(1):429–35.

Hebuterne X, Lemarie E, Michallet M, Montreuil CBd, Schneider SM, Goldwasser F. Prevalence of malnutrition and current use of nutrition support in patients with cancer. JPEN J Parenter Enteral Nutr. 2014;38(2):196–204.

Correia MITD. Nutrition screening vs nutrition assessment: what’s the difference? Nutr Clin Pract. 2017;33(1).

Wu B-W, Yin T, Cao W-X, Gu Z-D, Wang X-J, Yan M, et al. Clinical application of subjective global assessment in Chinese patients with gastrointestinal cancer. World J Gastrointest Oncol. 2009;15(28):3542–9.

Siregar BM. Gambaran status nutrisi pada pasien kanker di Poli Penyakit Dalam Divisi Hemato-Onkologi Medik RSUP H. Adam Malik pada Bulan September–November 2014 [Minor Thesis]. Medan: Universitas Sumatera Utara; 2014.

Kumar N. Assessment of malnutrition and nutritional therapy approaches in cancer patients. In: Kumar N, editor. Nutritional management of cancer treatment effects. Berlin, Heidelberg: Springer; 2012. p. 7–41.

Aoyagi T, Terracina KP, Raza A, Matsubara H, Takabe K. Cancer cachexia, mechanism and treatment. World J Gastrointest Oncol. 2015;7(4):17–29.

Silva FR, de Oliveira MG, Souza AS, Figueroa JN, Santos CS. Factors associated with malnutrition in hospitalized cancer patients: a croos-sectional study. Nutr J. 2015;14;123.

Aapro M, Arends J, Bozzetti F, Fearon K, Grunberg S, Herrstedt J, et al. Early recognition of malnutrition and cachexia in the cancer patient: a position paper of a European School of Oncology Task Force. Ann Oncol. 2014;25(8):1492–9.

Konturek PC, Herrmann HJ, Schink K, Neurath MF, Zopf Y. Malnutrition in Hospitals: It Was, Is Now, and Must Not Remain a Problem! Med Sci Monit. 2015;21:2969–75.

Nouh F, Omar M, Alshukri A, Younis M, Elmabsout A, Salem M, et al. Nutritional status of female breast cancer patients in Benghazi City of Libya. Sch J App Med Sci. 2017;5(6B):2179–87.

Arends J, Baracos V, Bertz H, Bozzetti F, Calder PC, Deutz NEP, et al. ESPEN expert group recommendations for action against cancer-related malnutrition. Clin Nutr. 2017(36):1187–96.

Gómez-Candela C, Albendea MAC, Milla SP, Arias RdP, Gómez JD, Rodríguez-Durán D, et al. Nutritional intervention in oncohematological patient. Nutr Hosp. 2012;27(3):669–80.


 This Journal indexed by


Creative Commons License
AMJ is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License


View My Stats