Incidence of Neonatal Hyperbilirubinemia based on Their Characteristics at Dr. Hasan Sadikin General Hospital Bandung Indonesia
Abstract
Background: Hyperbilirubinemia is the most frequent clinical condition that occurs in neonates identified by yellow discoloration of the skin and other tissues. It is caused by elevations of bilirubin level as the effect of increased breakdown of red blood cells, impaired conjugation of indirect bilirubin, and incomplete bilirubin excretion. This study was conducted to discribe the characteristics of neonates with hyperbilirubinemia.
Methods: This study used descriptive quantitative method which took retrospective data from medical record of neonates with hiperbilirubinemia in 2014. The population of this study was neonates which were born in the perinatology division at Dr. Hasan Sadikin General Hospital, Bandung. The variables collected were gender, gestational age, weight birth, general condition ad treatment options. The collected data were tabulated and presented by percentage and in the form of a table.
Results: One hundred and seventy four of 230 medical records of neonates with hyperbilirubinemia were collected based on the inclusion criteria. The results showed that 8.04% of 2,531 neonates born at Dr. Hasan Sadikin General Hospital in 2014 suffered from hyperbilirubinemia. Males (56.9%) were higher than females to have hyperbilirubinemia. Neonates born at term gestational age (55.2%) were more likely to have hyperbilirubinemia with low birth weight category (51.7%), healthy general condition (60.4%). The most treatment option was phototherapy (54.6%).
Conclusions: Most neonates with hyperbilirubinemia are males, who were born at aterm gestational age, with low birth weight. Most of the neonates are in healthy general condition and the most common treatment given to neonates is phototherapy.
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Sgro M, Campbell D, Shah V. Incidence and causes of severe neonatal hyperbilirubinemia in Canada. Can Med Assoc J. 2006;175(6):587–90.
Ben MD, Gazzin S, Tiribelli C. Neonatal hyperbilirubinemia. Ital J Ped. 2014;40(1):10–5
Wong RJ, Stevenson DK, Ahlfors CE, Vreman HJ. Neonatal jaundice bilirubin physiology and clinical chemistry. NeoReviews. 2007;8(2):58–67.
Juffrie M, Arief S, Rosalina I. Buku ajar gastroenterologi-hepatologi. Jakarta: Badan Penerbit IDAI; 2010. p.263–84.
Maisels MJ. What’s in a name? Physiologic and pathologic jaundice: the conundrum of defining normal bilirubin levels in the newborn. Pediatrics. 2006;118(2):805–7.
Cohen RS, Wong RJ, Stevenson DK. Understanding neonatal jaundice: a perspective on causation. Pediatrics & Neonatology. 2010;51(3):143–8.
Wang X, Chowdhury JR, Chowdhury NR. Bilirubin metabolism: applied physiology. Current Ped. 2006;16(1):70–4.
Croen LA, Yoshida CK, Odouli R, Newman TB. Neonatal hyperbilirubinemia and risk of autism spectrum disorders. Pediatrics. 2005;115(2):135–8.
Scrafford CG, Mullany LC, Katz J, Khatry SK, LeClerq SC, Darmstadt GL, et al. Incidence of and risk factors for neonatal jaundice among newborns in southern Nepal. Trop Med Int Health. 2013;18(11):1317–28.
Petrova A, Mehta R, Birchwood G, Ostfeld B, Hegyi T. Management of neonatal hyperbilirubinemia: pediatricians’ practices and educational needs. BMC pediatrics. 2006;6(1):6–15
Martin RJ, Fanaroff AA, Walsh MC. Fanaroff and martin’s neonatal-perinatal medicine. Philadelphia: Mosby;2011.
Widiasta A, Reniarti L, Sukadi A. Incidence of neonatal hyperbilirubinemia in low, intermediate-low, and intermediate-high risk group infants. Paediatr Indones; 2010;50(6):351–4
Maisels MJ, Bhutani VK, Bogen D, Newman TB, Stark AR, Watchko JF. Hyperbilirubinemia in the newborn infant ≥35 weeks’ gestation: an update with clarifications. Pediatrics. 2009;124(4):1193–8.
Onwuanaku CA, Okolo SN, Ige KO, Okpe SE, Toma BO. The effects of birth weight and gender on neonatal mortality in north central Nigeria. BMC study notes. 2011;4(1):562.
Tioseco JA, Milner, Patel K, Mohandes AAE. Does gender affect neonatal hyperbilirubinemia in infants? Pediatric Crit Care Med. 2011:6(2): 171–4.
Bhutani VK. Late preterm births: Major cause of prematurity and adverse outcomes of neonatal hyperbilirubinemia. Indian pediatrics. 2012;49(9):704–5.
Maisels MJ, Kring E. Length of stay, jaundice, and hospital readmission. Pediatrics. 2008;101(6):995–8.
Han S, Yu Z, Liu L, Wang J, Wei Q, Jiang C, et al. A Model for predicting significant hyperbilirubinemia in neonates from China. Pediatrics. 2015;136(4):896–905.
Vandborg PK, Hansen BM, Greisen G, Ebbesen F. Dose-response relationship of phototherapy for hyperbilirubinemia. Pediatrics. 2012;130(2):352–7.
Smitherman H, Stark AR, Bhutan VK, editors. Early recognition of neonatal hyperbilirubinemia and its emergent management. Seminars in Fetal and Neonatal Medicine. Amsterdam: Elsevier;2006.
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