Blood Glucose Level and HbA1C in Pediatric Patients with Diabetes Mellitus Type 1

Anisha Sefina Priatna; R. Mohamad Ryadi Fadil; Nugroho Harry Susanto

doi:10.15850/amj.v4n2.1074

Blood Glucose Level and HbA1C in Pediatric Patients with Diabetes Mellitus Type 1

Anisha Sefina Priatna, R. Mohamad Ryadi Fadil, Nugroho Harry Susanto

Abstract

Background: Diabetes mellitus (DM) is a common disease found all over the world, including Indonesia. The DM often found in pediatric patients is DM Type 1. The DM patients with uncontrolled blood glucose will likely suffer multiple organ damage, most notably to the kidneys, eyes, heart, and nerves. To help monitor blood glucose levels, lab checkups such as fasting blood glucose, 2 hours postprandial, and Hemoglobin A1C (HbA1C) levels are done. The aim of this study was to determine the profile of blood glucose and HbA1C in pediatric patients with DM Type 1.

Methods: The study was held in August to October 2014, using descriptive method and cross sectional design. Data were obtained from 28 medical records of DM Type 1 patients in the Department of Child Health at Dr. Hasan Sadikin General Hospital. The variables of this study were blood glucose level and HbA1 in three consecutive examinations. The collected data was presented in tables.

Results: The patients were 19 female and 9 male, most of the patients aged between 11–15 years old. Data reported that on first, second, and third examination, most subjects had both fasting blood glucose and 2 hours postprandial blood glucose levels over 180 mg/dl. On first and second HbA1c checkup, most subjects had values over 10%, and on third checkup had results ranging from 8 to 9.9%.

Conclusions: Most patients are girls and aged between 11–15 years old. The most have uncontrolled blood glucoselevel and HbA1c levels.

DOI: 10.15850/amj.v4n2.1074

Keywords

Blood glucose levels, HbA1C, diabetes mellitus type 1

Full Text:

PDF

References

Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27(5):1047–53.

Alemzadeh R, Ali O. Diabetes mellitus. In: Kliegman RM, editors. Kliegman: nelson textbook of pediatrics. 19th ed. Philadelphia: Elsevier-Saunders; 2011. p. 1968–93.

Aman Pulungan, Herqutanto. Diabetes melitus tipe 1: “penyakit baru” yang akan makin akrab dengan kita. Maj Kedokt Indon. 2009;59(10):455–458.

American Diabetes Associaton. Standards of medical care in diabetes—2014. Diabetes Care. 2014;37(Suppl1):S14–80.

American Diabetes Associaton. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010;33(Suppl1):S62–69.

Day A. HbA1c and diagnosis of diabetes: the test has finally come of age. Ann Clin Biochem. 2012;49(1):7–8.

Cohen RM, Haggerty S, Herman WH. HbA1c for the diagnosis of diabetes and prediabetes: is it time for a mid-course correction?. J Clin Endocrinol Metab. 2010;95(12):5203–6.

Alqahtani N, Khan WA, Alhumaidi MH, Ahmed YA. Use of glycated hemoglobin in diagnosis of diabetes mellitus and pre-diabetes and role of fasting plasma glucose, oral glucose tolerance test. Int J Prev Med.2013;4(9):1025–9.

Maahs DM, West NA, Lawrence JM, Mayer-Davis EJ. Epidemiology of type 1 diabetes. Endocrinol Metab Clin North Am. 2010;39(3):481–97.

Battelino T, Phillip M, Bratina N, Nimri R, Oskarsson P, Bolinder J. Effect of continuous glucose monitoring on hypoglycemia in type 1 diabetes. Diabetes Care. 2011;34(4):795–800.

DOI: https://doi.org/10.15850/amj.v4n2.1074