Cerebrospinal Fluid Characteristics in Tuberculous Meningitis with Hydrocephalus in Department of Neurosurgery, Dr. Hasan Sadikin General Hospital, Bandung in the Period of 2014–2016

Astrid Tamara Maajid Budiman, Nida Suryana, Ahmad Faried, Ida Parwati

Abstract


Objectives: To describe the cerebrospinal fluid (CSF) findings in tuberculous meningitis (TBM) with hydrocephalus as diagnostic criteria of TBM.

Methods: The research design was descriptive cross sectional using retrospective method. The data were obtained from medical record of TBM with hydrocephalus patients treated in Department of Neurosurgery Dr. Hasan Sadikin General Hospital, Bandung from January 2014–September 2016.

Results: Sixty one samples were included in the study. The patient characteristics such as age, gender, and CSF laboratory features: color and clarity, cells and differential count, protein and glucose were recorded. The majority of CSF macroscopic appearance was clear (88.5%) and colorless (88.5%). The median of CSF cell count was 25 cells/mm3 with lymphocyte predominance (median: 76%). Increased protein from normal value range was seen in CSF (median: 50 mg/dL), besides, the mean of CSF glucose in this study remained in its normal value range (mean: 58.9±26.68 mg/dL) with lower CSF to blood glucose ratio (mean: 0.41±0.27).

Conclusion: Clear CSF and colorless appearance, lymphocyte pleocytosis, high protein, and low CSF glucose:blood glucose ratio remain as typical CSF of TBM patient characteristics in Department of Neurosurgery, Dr. Hasan Sadikin General Hospital, Bandung.

Keywords: Cerebrospinal fluid, hydrocephalus, tuberculous meningitis

Keywords


Cerebrospinal fluid, hydrocephalus, tuberculous meningitis

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