Relationship between Neutrophil-Lymphocyte Ratio and Cardiac Autonomic Neuropathy in Diabetes Mellitus Type 2 Patients

Cahyandari Nurlaelatiningsih, Sunaryo Sastradimaja Barki Sastradimaja, Irma Ruslina Defi

Abstract


Objective: To analyze the relationship between cardiac autonomic neuropathy (CAN) and neutrophil-lymphocyte ratio (NLR) in DM type 2 patients. The Ewing test is regarded as an assessment to diagnose CAN by examining cardiac autonomic functions based on heart rate and blood pressure in related physiologic maneuvers. However, the examination is considered not practically effective.

Methods: This was a cross-sectional study which was conducted at Department of Internal Medicine Polyclinic, Dr. Hasan Sadikin General Hospital, Bandung and Chronic Disease Management (CDM) Club in Garut Regency, West Java, Indonesia in the period of October to December 2015. Subjects in the study were 57 DM type 2 patients who met the inclusion criteria. Cardiac autonomic neuropathy examination and complete blood count (CBC) were performed to discover neutrophil-lymphocyte ratio in the subjects.

Results: Based on Rank Spearman correlation test, the relationship between CAN in DM type 2 patients and NLR was considered statistically significant (r=0.679; p=0.000) and NLR to CAN cut off point was 1.34.

Conclusions: There was a relationship between CAN and DM type 2 diagnosis duration (r=0.3188; p=0.0188).

Keywords: Cardiac autonomic neuropathy, diabetes mellitus type 2, Ewing test, neutrophil-lymphocyte ratio

 

DOI: 10.15850/ijihs.v5n1.961


Keywords


Cardiac autonomic neuropathy, diabetes mellitus type 2, Ewing test, neutrophil-lymphocyte ratio

Refbacks

  • There are currently no refbacks.




This journal indexed on:

                

  

Creative Commons License
IJIHS is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License



View My Stats