Ratio of Monocytes to Lymphocytes from Peripheral Blood among Tuberculous Meningitis Patients with HIV Infection in Tertiary Hospital-West Java

Ridha Amalia, Dewi Kartika Turbawaty, Adhi Kristianto Sugianli, Siti Aminah

Abstract


Objective: To describe the ratio of monocytes to lymphocytes (ML) in peripheral blood among tuberculous meningitis patients with Human Immunodeficiency Virus (HIV) infection in Dr. Hasan Sadikin General Hospital, Bandung as tertiary hospital in West Java, Indonesia.

 

Method: A retrospective study with descriptive design was done in Dr. Hasan Sadikin General Hospital, Bandung. Data were collected from medical record of tuberculous meningitis patients who were hospitalized in Dr. Hasan Sadikin General Hospital, Bandung in 2014–2016. The sample size was determined by using total sampling method. From 280 data, 195 subjects were excluded due to incomplete data, therefore, 85 subjects remained.

Result: Overall from 85 subjects, there were 22 patients (25.9%) had ML ratio ≤25th percentile, 41 people (48.2%) had ML ratio between 25th percentile–75thpercentile, 22 people (25.9%) had ML ratio ≥75th percentile.

 

Conclusion: Change in hematological profile could indicate a disease process. This study showed that description of ML ratio in tuberculous meningitis patients with HIV infection has a significant rise hencecould be used as a predictor for development of tuberculous meningitis in HIV-infected people.

 

Keywords: Human immunodeficiency virus infection,lymphocyte, monocyte, monocyte to lymphocyte ratio, tuberculous meningitis

Keywords


Human immunodeficiency virus infection,lymphocyte, monocyte, monocyte to lymphocyte ratio, tuberculous meningitis

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